Kuhseng Extract Sophora flavescens Oxymatrine Matrine

Ku Shen is a Chinese herb with a lot of promise. Although it has been used by traditional practitioners for thousands of years, it is now the subject of some very exciting clinical and pharmacological research, revealing its powerful therapeutic value for a surprisingly wide range of conditions - from dysentery and asthma to cancer and hepatitis.

Ku Shen is the Chinese term for the root of Sophora flavescens, a member of the Bean and Pea family, Leguminosae. Found growing wild throughout China in sunny meadows and roadsides, it is also cultivated, mostly in the Shanxi and Hubei provinces. While the plant contains a rich cornucopia of useful chemical constituents, as most herbs do, current research is focused primarily on 2 of its quinolizodine alkaloid constituents, matrine and oxymatrine. S. flavescens naturally contains about 2% of these compounds in its root stock.

Other species of Sophora also contain these valuable constituents. S. japonica and S. angustifolia are also called Ku Shen in the Chinese Pharmacopeia, because in Traditional Chinese Medicine, they were found to have properties and applications nearly equivalent to those of S. flavescens. S. subprostrata is also quite similar but is distinguished as Shan Dou Gen. Both types of TCM herb are bitter, cold "heat clearing" herbs, but Ku Shen is thought to "dry dampness" whereas Shan Dou Gen is thought to "clean toxins." S. alopecuroides is also used in traditional medicine. Of all the alkaloid rich Sophoras, though, S. flavescens is most common and most commonly used. It is much like the usage prevalence of Echinacea purpurea over its cousins in the United States.

Matrine

CAS: 519-02-8

Molecular formula: C15H24N2O

Molecrular weight: 248.37

Brief: White powder

Purity: 98% by HPLC

Matrine Liquid

CAS: 519-02-8

Molecular formula: C15H24N2O

Molecrular weight: 248.37

Brief: Brown yellow powderand Brown liquld

Purity: 0.6% 1% 2% 4% by HPLC

Oxymatrine 98%

Synonyms: Matrine N-oxide

CAS: 16837-52-8

Molecular formula: C15H24N2O2

Molecrular weight: 264.36

Brief: White powder

Purity: 98% by HPLC

Best price matrine natural insecticide Description:

Sophora flavescens is a species of plant in the genus Sophora. Ku shen (the root) or kushenin (a flavonoid compound) is a typical traditional Chinese medicine that is found in this plant. It is commonly used for the treatment of viral hepatitis, enteritis,

cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases (such as colpitis, psoriasis and eczema). Its roots contain quinolizidine alkaloids, includying matrine and its oxide, matrine oxide that interfere TNF-alpha and IL-6, suggesting that oxymatrine may inhibit the expression of the above pro-inflammatory cytokines. Matrine also inhibited expression of Substance P and NK-1R in a human model of skin inflammation, as well as acting as an agonist at mu and kappa opioid receptors.

Matrine is an alkaloid found in plants from the Sophora family. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.Matrine possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. Matrine is a component of the traditional Chinese medical herb Sophora flavescens Ait. Matrine and the related compound oxymatrine have an antifeedant effect against Formosan subterranean termite.